Ammonium Thioglycolate CAS 5421-46-5 - Buy from China Suppliers & Factory | Colorless Liquid, Free Samples Available
Typical Properties
| Item | Specifications |
| Appearance | Colorless or Lavender Pink |
| Purity | 50%; 60%; 70% |
| pH | 6.0–6.8 (25℃) |
| Specific Gravity (ρ20, g/cm³) | 1.24 (25℃) |
Ammonium Thioglycolate (also known as Ammonium Thioethanolate) is a highly efficient reducing thiol compound. Its core function is to cleave the disulfide bonds in keratin, making it a key raw material for cold wave perms, hair straightening, and depilatories. It is also utilized in fields such as metal corrosion inhibition and chemical analysis.
Product Advantages
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1Strong Reducing Power & Precision: Selectively cleaves disulfide bonds in hair keratin, delivering significant softening and reshaping effects.
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2Neutral & Mild: With a pH close to that of human skin and hair, it is less irritating than traditional thioglycolic acid and causes minimal damage to hair quality.
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3Excellent Water Solubility: Easy to formulate into various aqueous solutions and creams, offering good compatibility with different formulations.
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4Flexible Application: Action intensity can be adjusted via concentration and pH, making it suitable for diverse scenarios such as perming, hair straightening, and depilatory uses.
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5Multifunctionality: Beyond hair care, it serves as a metal corrosion inhibitor, chemical analysis reagent, and thiolating agent.
Application Areas
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Hair Care Industry (Core Application)
- ●Cold Wave Lotions / Perm Solutions: Softens hair keratin and reshapes disulfide bonds to achieve permanent curling; serves as the core reducing agent in cold perms.
- ●Hair Straightening Creams / Relaxers: Cleaves disulfide bonds to soften hair, working in conjunction with neutralizers to achieve permanent straightening.
- ●Depilatory Creams / Lotions: Softens body hair keratin to facilitate easy removal; the preferred choice for mild depilatory products.
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💡 Recommended Concentration: 5%–15% for perming/straightening; 2%–8% for depilatory use.
2
Industrial & Other Fields
- ●Metal Corrosion Inhibition: Forms a protective FeS film in high-temperature brine/completion fluids to inhibit carbon steel corrosion (140–200℃).
- ●Chemical Analysis: Used as a masking agent and reducing agent for the photometric determination of ions such as iron, aluminum, silver, and tin.
- ●Material Modification: Serves as a thiolating agent for the preparation of adsorption materials and functional polymers.
- ●Electronic Cleaning: Acts as an auxiliary agent for metal surface treatment and cleaning.
Package & Storage
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Package
25 kg/drum | 200 kg/drum
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Storage
Store in a cool, dry, and dark place, preferably refrigerated at 2–8℃. Avoid contact with iron/copper.
Frequently Asked Questions
Q What is Ammonium Thioglycolate and how does it work?
Ammonium Thioglycolate (also known as Ammonium Thioethanolate) is a highly efficient reducing thiol compound. It works by selectively cleaving the disulfide bonds in hair keratin, which softens and reshapes the hair structure. This mechanism is the foundation for its use in cold wave perms, hair straightening, and depilatory products.
Q What concentrations are available and which should I choose?
Ammonium Thioglycolate is available in three purity grades: 50%, 60%, and 70%. For perming and hair straightening applications, a working concentration of 5%–15% is recommended. For depilatory creams and lotions, a lower concentration of 2%–8% is typically sufficient. The appropriate grade depends on your formulation requirements and desired action intensity.
Q Is Ammonium Thioglycolate safe for use in cosmetic formulations?
Yes. Ammonium Thioglycolate has a pH range of 6.0–6.8, which is close to the natural pH of human skin and hair. This makes it significantly milder and less irritating than traditional thioglycolic acid. When used within recommended concentrations, it causes minimal damage to hair quality and is widely accepted in professional cosmetic formulations.
Q Can Ammonium Thioglycolate be used outside of the cosmetics industry?
Absolutely. Beyond hair care, Ammonium Thioglycolate has important industrial applications. It is used as a metal corrosion inhibitor in high-temperature brine and completion fluids (140–200℃), as a masking and reducing agent in chemical analysis, as a thiolating agent in material modification, and as an auxiliary agent in electronic cleaning and metal surface treatment.
Q What are the packaging options and how should the product be stored?
The product is available in 25 kg/drum and 200 kg/drum packaging options to suit different order volumes. For proper storage, keep the product in a cool, dry, and dark environment. Refrigeration at 2–8℃ is preferred to maintain product stability. It is important to avoid any contact with iron or copper, as these metals can degrade the product.
Q How does Ammonium Thioglycolate compare to traditional thioglycolic acid?
Compared to traditional thioglycolic acid, Ammonium Thioglycolate offers a more neutral and milder profile due to its pH being closer to that of skin and hair. It is less irritating, causes less damage to hair quality, and provides excellent water solubility for easier formulation. Its action intensity can also be flexibly adjusted by modifying concentration and pH, making it more versatile for a wider range of applications.





