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Ammonium Thioglycolate CAS 5421-46-5 - China Suppliers and Factory Direct Sales of Quality Chemicals
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Ammonium Thioglycolate CAS 5421-46-5 - China Suppliers and Factory Direct Sales of Quality Chemicals

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Chemical Name: Ammonium thioglycolate 
CAS No.: 5421-46-5
Molecular Formula: C2H4O2S.H3N
Molecular Structure:

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Molecular Weight: 109.15
Appearance: Colorless liquid 
Sample: Free samples are available
Melting Point: 139-139.5 °C
Boiling Point: 115 ℃ [at 101 325 Pa]
Density: 1.22

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As a leading factory and suppliers of Ammonium thioglycolate in China, we provide high-quality chemicals for various applications. Our product is known for its excellent purity and reliability, making it a top choice for industries requiring precise chemical formulations. Get in touch with us for free samples and experience our commitment to quality.

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    Typical Properties
    Item Specifications
    Appearance Colorless or Lavender Pink
    Purity 50%; 60%; 70%
    PH 6.0–6.8 (25℃)
    Specific Gravity (ρ20, g/cm³) 1.24 (25℃)
    Ammonium Thioglycolate (also known as Ammonium Thioethanolate) is a highly efficient reducing thiol compound. Its core function is to cleave the disulfide bonds in keratin, making it a key raw material for cold wave perms, hair straightening, and depilatories. It is also utilized in fields such as metal corrosion inhibition and chemical analysis.
    Product Advantages
    1
    Strong Reducing Power & Precision: Selectively cleaves disulfide bonds in hair keratin, delivering significant softening and reshaping effects.
    2
    Neutral & Mild: With a pH close to that of human skin and hair, it is less irritating than traditional thioglycolic acid and causes minimal damage to hair quality.
    3
    Excellent Water Solubility: Easy to formulate into various aqueous solutions and creams, offering good compatibility with different formulations.
    4
    Flexible Application: Action intensity can be adjusted via concentration and pH, making it suitable for diverse scenarios such as perming, hair straightening, and depilatory uses.
    5
    Multifunctionality: Beyond hair care, it serves as a metal corrosion inhibitor, chemical analysis reagent, and thiolating agent.
    Application Areas
    1. Hair Care Industry (Core Application)
    Cold Wave Lotions / Perm Solutions: Softens hair keratin and reshapes disulfide bonds to achieve permanent curling; serves as the core reducing agent in cold perms.
    Hair Straightening Creams / Relaxers: Cleaves disulfide bonds to soften hair, working in conjunction with neutralizers to achieve permanent straightening.
    Depilatory Creams / Lotions: Softens body hair keratin to facilitate easy removal; the preferred choice for mild depilatory products.
    Recommended Concentration: 5%–15% for perming/straightening; 2%–8% for depilatory use.
    2. Industrial & Other Fields
    Metal Corrosion Inhibition: Forms a protective FeS film in high-temperature brine/completion fluids to inhibit carbon steel corrosion (140–200℃).
    Chemical Analysis: Used as a masking agent and reducing agent for the photometric determination of ions such as iron, aluminum, silver, and tin.
    Material Modification: Serves as a thiolating agent for the preparation of adsorption materials and functional polymers.
    Electronic Cleaning: Acts as an auxiliary agent for metal surface treatment and cleaning.
    Package & Storage
    📦
    Package
    25 kg/drum, 200 kg/drum
    🌡️
    Storage
    Store in a cool, dry, and dark place, preferably refrigerated at 2–8℃. Avoid contact with iron/copper.
    Frequently Asked Questions
    Q1 What is Ammonium Thioglycolate and what is it primarily used for?
    Ammonium Thioglycolate (also known as Ammonium Thioethanolate) is a highly efficient reducing thiol compound. It is primarily used in the hair care industry for cold wave perms, hair straightening, and depilatory creams. It works by cleaving the disulfide bonds in hair keratin, enabling the hair to be reshaped or removed.
    Q2 What concentrations of Ammonium Thioglycolate are available, and which should I choose?
    Ammonium Thioglycolate is available in 50%, 60%, and 70% purity grades. For perming and hair straightening applications, a working concentration of 5%–15% is recommended. For depilatory products, 2%–8% is typically sufficient. The appropriate grade depends on your formulation requirements and desired action intensity.
    Q3 Is Ammonium Thioglycolate safe for use on hair and skin?
    Yes, when used at recommended concentrations. Its pH (6.0–6.8) is close to that of human skin and hair, making it milder and less irritating than traditional thioglycolic acid. It causes minimal damage to hair quality when properly formulated. Always follow recommended usage concentrations for consumer safety.
    Q4 Can Ammonium Thioglycolate be used in industrial applications?
    Yes. Beyond hair care, Ammonium Thioglycolate is used as a metal corrosion inhibitor in high-temperature brine and completion fluids (effective at 140–200℃), as a masking and reducing agent in chemical analysis, as a thiolating agent for material modification, and as an auxiliary agent in electronic metal surface cleaning.
    Q5 How should Ammonium Thioglycolate be stored to maintain its quality?
    It should be stored in a cool, dry, and dark environment, preferably refrigerated at 2–8℃. Direct contact with iron or copper must be avoided, as these metals can catalyze degradation. Proper storage ensures the product maintains its reducing activity and shelf stability.
    Q6 What packaging options are available for Ammonium Thioglycolate?
    Ammonium Thioglycolate is available in two standard packaging options: 25 kg drums for smaller-scale or laboratory use, and 200 kg drums for bulk industrial procurement. Custom packaging arrangements may be discussed based on order volume and logistics requirements.

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