Ammonium Thioglycolate CAS 5421-46-5 - China Suppliers & Factory for Quality Chemical Products
Typical Properties
| Item | Specifications |
| Appearance | Colorless or Lavender Pink |
| Purity | 50%; 60%; 70% |
| PH | 6.0–6.8 (25℃) |
| Specific Gravity (ρ20, g/cm³) | 1.24 (25℃) |
Ammonium Thioglycolate (also known as Ammonium Thioethanolate) is a highly efficient reducing thiol compound. Its core function is to cleave the disulfide bonds in keratin, making it a key raw material for cold wave perms, hair straightening, and depilatories. It is also utilized in fields such as metal corrosion inhibition and chemical analysis.
Product Advantages
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1Strong Reducing Power & Precision: Selectively cleaves disulfide bonds in hair keratin, delivering significant softening and reshaping effects.
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2Neutral & Mild: With a pH close to that of human skin and hair, it is less irritating than traditional thioglycolic acid and causes minimal damage to hair quality.
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3Excellent Water Solubility: Easy to formulate into various aqueous solutions and creams, offering good compatibility with different formulations.
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4Flexible Application: Action intensity can be adjusted via concentration and pH, making it suitable for diverse scenarios such as perming, hair straightening, and depilatory uses.
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5Multifunctionality: Beyond hair care, it serves as a metal corrosion inhibitor, chemical analysis reagent, and thiolating agent.
Application Areas
1. Hair Care Industry (Core Application)
- Cold Wave Lotions / Perm Solutions: Softens hair keratin and reshapes disulfide bonds to achieve permanent curling; serves as the core reducing agent in cold perms.
- Hair Straightening Creams / Relaxers: Cleaves disulfide bonds to soften hair, working in conjunction with neutralizers to achieve permanent straightening.
- Depilatory Creams / Lotions: Softens body hair keratin to facilitate easy removal; the preferred choice for mild depilatory products.
- Recommended Concentration: 5%–15% for perming/straightening; 2%–8% for depilatory use.
2. Industrial & Other Fields
- Metal Corrosion Inhibition: Forms a protective FeS film in high-temperature brine/completion fluids to inhibit carbon steel corrosion (140–200℃).
- Chemical Analysis: Used as a masking agent and reducing agent for the photometric determination of ions such as iron, aluminum, silver, and tin.
- Material Modification: Serves as a thiolating agent for the preparation of adsorption materials and functional polymers.
- Electronic Cleaning: Acts as an auxiliary agent for metal surface treatment and cleaning.
Package & Storage
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Package
25 kg/drum | 200 kg/drum
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Storage
Store in a cool, dry, and dark place, preferably refrigerated at 2–8℃. Avoid contact with iron/copper.
Frequently Asked Questions
What is Ammonium Thioglycolate and what is it primarily used for?
Ammonium Thioglycolate (also known as Ammonium Thioethanolate) is a highly efficient reducing thiol compound. It is primarily used in the hair care industry as the core reducing agent in cold wave perms, hair straightening creams, and depilatory products. It is also applied in metal corrosion inhibition and chemical analysis.
What concentrations of Ammonium Thioglycolate are available?
Ammonium Thioglycolate is available in three standard purity levels: 50%, 60%, and 70%, allowing formulators to choose the most suitable concentration for their specific applications.
What is the recommended usage concentration for hair perming and depilatory applications?
For perming and hair straightening applications, a concentration of 5%–15% is recommended. For depilatory cream and lotion formulations, a lower concentration of 2%–8% is typically used to ensure a milder effect on the skin.
Is Ammonium Thioglycolate safe for skin contact in cosmetic formulations?
Ammonium Thioglycolate has a pH of 6.0–6.8, which is close to the natural pH of human skin and hair. This makes it significantly less irritating than traditional thioglycolic acid, resulting in minimal damage to hair quality when used at recommended concentrations in properly formulated products.
How should Ammonium Thioglycolate be stored to maintain its stability?
It should be stored in a cool, dry, and dark environment, preferably refrigerated at 2–8℃. Direct contact with iron or copper materials must be avoided, as these metals can catalyze decomposition and reduce product quality.
Can Ammonium Thioglycolate be used in industrial applications beyond cosmetics?
Yes. Beyond its use in hair care, Ammonium Thioglycolate is utilized as a metal corrosion inhibitor in high-temperature brine and completion fluids (140–200℃), as a masking and reducing agent in chemical analysis, as a thiolating agent for functional polymer preparation, and as an auxiliary agent in electronic metal surface cleaning.





