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Ammonium Thioglycolate CAS 5421-46-5 - Trusted China Suppliers & Factory for Quality Chemicals
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Ammonium Thioglycolate CAS 5421-46-5 - Trusted China Suppliers & Factory for Quality Chemicals

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Chemical Name: Ammonium thioglycolate 
CAS No.: 5421-46-5
Molecular Formula: C2H4O2S.H3N
Molecular Structure:

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Molecular Weight: 109.15
Appearance: Colorless liquid 
Sample: Free samples available for evaluation
Melting Point: 139-139.5 °C
Boiling Point: 115 °C [at 101 325 Pa]
Density: 1.22

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As a leading supplier of Ammonium thioglycolate in China, we pride ourselves on providing high-quality products directly from our advanced factory. Our colorless liquid offers reliable performance and purity, making it an essential ingredient for various applications. We invite you to request free samples to experience the quality for yourself.

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    Typical Properties
    Item Specifications
    Appearance Colorless or Lavender Pink
    Purity 50%; 60%; 70%
    PH 6.0–6.8 (25℃)
    Specific Gravity (ρ20, g/cm³) 1.24 (25℃)
    Ammonium Thioglycolate (also known as Ammonium Thioethanolate) is a highly efficient reducing thiol compound. Its core function is to cleave the disulfide bonds in keratin, making it a key raw material for cold wave perms, hair straightening, and depilatories. It is also utilized in fields such as metal corrosion inhibition and chemical analysis.
    Product Advantages
    • 1 Strong Reducing Power & Precision: Selectively cleaves disulfide bonds in hair keratin, delivering significant softening and reshaping effects.
    • 2 Neutral & Mild: With a pH close to that of human skin and hair, it is less irritating than traditional thioglycolic acid and causes minimal damage to hair quality.
    • 3 Excellent Water Solubility: Easy to formulate into various aqueous solutions and creams, offering good compatibility with different formulations.
    • 4 Flexible Application: Action intensity can be adjusted via concentration and pH, making it suitable for diverse scenarios such as perming, hair straightening, and depilatory uses.
    • 5 Multifunctionality: Beyond hair care, it serves as a metal corrosion inhibitor, chemical analysis reagent, and thiolating agent.
    Application Areas
    1 Hair Care Industry (Core Application)
    • Cold Wave Lotions / Perm Solutions: Softens hair keratin and reshapes disulfide bonds to achieve permanent curling; serves as the core reducing agent in cold perms.
    • Hair Straightening Creams / Relaxers: Cleaves disulfide bonds to soften hair, working in conjunction with neutralizers to achieve permanent straightening.
    • Depilatory Creams / Lotions: Softens body hair keratin to facilitate easy removal; the preferred choice for mild depilatory products.
    Recommended Concentration: 5%–15% for perming/straightening  |  2%–8% for depilatory use
    2 Industrial & Other Fields
    • Metal Corrosion Inhibition: Forms a protective FeS film in high-temperature brine/completion fluids to inhibit carbon steel corrosion (140–200℃).
    • Chemical Analysis: Used as a masking agent and reducing agent for the photometric determination of ions such as iron, aluminum, silver, and tin.
    • Material Modification: Serves as a thiolating agent for the preparation of adsorption materials and functional polymers.
    • Electronic Cleaning: Acts as an auxiliary agent for metal surface treatment and cleaning.
    Package & Storage
    📦
    Package
    25 kg/drum  |  200 kg/drum
    ❄️
    Storage
    Cool, dry & dark place; refrigerate at 2–8℃; avoid contact with iron/copper
    Frequently Asked Questions
    Q What is Ammonium Thioglycolate and what is it primarily used for?
    Ammonium Thioglycolate (also known as Ammonium Thioethanolate) is a highly efficient reducing thiol compound. It is primarily used to cleave disulfide bonds in hair keratin, making it a core ingredient in cold wave perm solutions, hair straightening creams, and depilatory products. It also finds applications in metal corrosion inhibition and chemical analysis.
    Q What concentration of Ammonium Thioglycolate is recommended for perming and hair straightening?
    For perming and hair straightening applications, a concentration of 5%–15% is generally recommended. For depilatory cream formulations, a lower concentration of 2%–8% is typically sufficient and preferred for a milder effect.
    Q Is Ammonium Thioglycolate safer than traditional thioglycolic acid for hair care use?
    Yes. Ammonium Thioglycolate has a pH close to that of human skin and hair, making it less irritating than traditional thioglycolic acid. It causes minimal damage to hair quality, making it the preferred choice for mild and modern hair care formulations.
    Q What are the available purity grades and packaging options?
    Ammonium Thioglycolate is available in three purity grades: 50%, 60%, and 70%. It is supplied in two packaging options — 25 kg/drum and 200 kg/drum — to accommodate both small-scale and bulk industrial requirements.
    Q How should Ammonium Thioglycolate be stored to maintain its quality?
    It should be stored in a cool, dry, and dark environment. Refrigeration at 2–8℃ is preferred to preserve product stability. Direct contact with iron or copper materials must be avoided, as these metals can catalyze decomposition and reduce product quality.
    Q Can Ammonium Thioglycolate be used in industrial applications beyond hair care?
    Absolutely. Beyond hair care, Ammonium Thioglycolate is used as a metal corrosion inhibitor in high-temperature brine and completion fluids (140–200℃), as a masking and reducing agent in chemical analysis, as a thiolating agent for functional polymer preparation, and as an auxiliary agent in electronic metal surface cleaning treatments.

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