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Ascorbyl Tetraisopalmitate CAS 183476-82-6 - China Suppliers and Factory for Quality Skincare Ingredients
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Chemical Name: Ascorbyl Tetraisopalmitate
CAS No.: 183476-82-6
Molecular Formula: C70H128O10
Molecular Structure:
Molecular Weight: 1129.76
Appearance: Colorless Transparent Liquid
Sample: Free samples are available
As a leading manufacturer and supplier of Ascorbyl Tetraisopalmitate in China, our factory ensures the highest quality standards for this powerful antioxidant. This versatile compound is renowned for its skin-brightening properties and is commonly used in cosmetic formulations. Trust our Chinese factory for premium quality and reliable supply to meet your needs.
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Typical Properties
| Item | Specifications |
| Appearance | Colorless Transparent Liquid |
| Color (APHA) | 100 max |
| Assay | 98~102% |
| Refractive index (25℃) | 1.459~1.465 |
| Specific gravity | 0.930~0.943 |
| Heavy metals | NMT 10 ppm |
| Arsenic | NMT 2 ppm |
| Microbial limited tests | Bacteria <500 cfu/g |
| Mildew and microzyme <100 cfu/g | |
| No escherichia coli should be found |
Application
As an efficient and gentle whitening and anti-aging core ingredient, VC-IP is the preferred ingredient for high-end efficacy skincare, suitable for all skin types, including sensitive skin and niacinamide intolerant skin. Its transdermal absorption rate is 16.5 times that of water-soluble vitamin C, which can quickly penetrate the stratum corneum and be hydrolyzed into active vitamin C by enzymes in the skin, continuously exerting its effects. Its formula compatibility is extremely strong, making it one of the core ingredients in the trend of "oil nourishing skin".
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1. Whitening and spot lightening: Accurately inhibit the activity of tyrosinase, block the generation of melanin from the source, effectively improve the dull skin color, anti tanning after sun exposure, acne marks and spots after inflammation. Long term use can achieve even and bright skin color, which has been listed as the legal whitening active ingredient in Japan, South Korea and Taiwan, China.
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2. Antioxidant and anti-aging: Efficiently removes free radicals, prevents skin lipid peroxidation, reduces UV damage to cellular DNA, and provides photoprotection; simultaneously promoting collagen synthesis in the dermis, inhibiting matrix metalloproteinase activity, improving fine and dry lines, enhancing skin elasticity and firmness, and resisting photoaging.
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3. Gentle repair: Extremely low irritation, with a risk factor of only 1, no need to establish tolerance, can soothe the skin, maintain the integrity of the skin barrier, adapt to daily care of sensitive skin, and also have the effect of softening the skin, enhancing the skin feel of skincare products.
🧴 Common application products: High-end whitening essence oil, anti-aging essence, face cream, lotion, sunscreen products, post sun repair products, facial mask, especially suitable for "oil skin care" dosage forms. Can work together with nicotinamide, vitamin E derivatives, bose, peptides and other ingredients to enhance the efficacy of the product.
📏 Recommended dosage: 0.1%–2.0% is recommended for resident products (face cream, essence), and the CIR assessment of the United States believes that the concentration is not higher than 4%, which is safe for use. It is recommended to add no more than 0.05% to cleansing and shampoo products, and to further enhance stability by combining 0.1–0.3% tocopherol and disodium EDTA in the formula.
Package
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Available packaging sizes:
1kg / 5kg / 20kg / bottle
1kg / 5kg / 20kg / bottle
Storage
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Store in a cool, dry, and well-ventilated place, away from light and sealed.
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Keep away from strong acids, alkalis, and oxidants. Avoid mixing with odors and volatile chemicals.
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When stacking, keep away from the ground and walls to prevent moisture.
Frequently Asked Questions
Q What is VC-IP and how does it differ from regular Vitamin C?
VC-IP (Ascorbyl Tetraisopalmitate) is an oil-soluble form of Vitamin C. Unlike water-soluble Vitamin C (L-ascorbic acid), VC-IP offers significantly higher skin penetration — up to 16.5 times greater transdermal absorption — and superior stability in formulations, making it far more effective in delivering active Vitamin C into the deeper layers of the skin.
Q Is VC-IP suitable for sensitive skin?
Yes. VC-IP has an extremely low irritation profile with a risk factor of only 1. It does not require a tolerance-building period and is gentle enough for daily use on sensitive skin, including skin that is intolerant to niacinamide.
Q What is the recommended usage concentration of VC-IP in skincare formulations?
For leave-on products such as face creams and serums, a concentration of 0.1%–2.0% is recommended. The U.S. CIR (Cosmetic Ingredient Review) considers concentrations up to 4% safe. For rinse-off products like cleansers and shampoos, no more than 0.05% is advised.
Q Can VC-IP be combined with other active ingredients?
Absolutely. VC-IP has excellent formula compatibility and works synergistically with nicotinamide, vitamin E derivatives, bose, peptides, and other skincare actives. To further enhance stability in formulations, it is recommended to combine with 0.1–0.3% tocopherol and disodium EDTA.
Q Is VC-IP a legally recognized whitening ingredient?
Yes. VC-IP has been officially listed as a legal whitening active ingredient in Japan, South Korea, and Taiwan, China. It works by accurately inhibiting tyrosinase activity to block melanin production at the source, effectively reducing dark spots, post-inflammatory hyperpigmentation, and uneven skin tone.
Q What are the storage requirements for VC-IP?
VC-IP should be stored in a cool, dry, and well-ventilated environment, away from direct light and in sealed containers. It must be kept away from strong acids, alkalis, and oxidants, and should not be stored alongside volatile chemicals or odorous substances. Containers should be elevated off the ground and away from walls to prevent moisture exposure.