Ascorbyl Tetraisopalmitate CAS 183476-82-6 - High-Quality Supplier from China Factory, Colorless Liquid Available
Typical Properties
| Item | Specifications |
| Appearance | Colorless Transparent Liquid |
| Color (APHA) | 100 max |
| Assay | 98~102% |
| Refractive Index (25℃) | 1.459~1.465 |
| Specific Gravity | 0.930~0.943 |
| Heavy Metals | NMT 10 ppm |
| Arsenic | NMT 2 ppm |
| Microbial Limited Tests | Bacteria < 500 cfu/g |
| Mildew and Microzyme < 100 cfu/g | |
| No Escherichia coli should be found |
Application
As an efficient and gentle whitening and anti-aging core ingredient, VC-IP is the preferred ingredient for high-end efficacy skincare, suitable for all skin types, including sensitive skin and niacinamide intolerant skin. Its transdermal absorption rate is 16.5 times that of water-soluble vitamin C, which can quickly penetrate the stratum corneum and be hydrolyzed into active vitamin C by enzymes in the skin, continuously exerting its effects. Its formula compatibility is extremely strong, making it one of the core ingredients in the trend of "oil nourishing skin."
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1. Whitening and Spot Lightening Accurately inhibit the activity of tyrosinase, block the generation of melanin from the source, effectively improve the dull skin color, anti tanning after sun exposure, acne marks and spots after inflammation. Long term use can achieve even and bright skin color, which has been listed as the legal whitening active ingredient in Japan, South Korea and Taiwan, China.
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2. Antioxidant and Anti-Aging Efficiently removes free radicals, prevents skin lipid peroxidation, reduces UV damage to cellular DNA, and provides photoprotection. Simultaneously promoting collagen synthesis in the dermis, inhibiting matrix metalloproteinase activity, improving fine and dry lines, enhancing skin elasticity and firmness, and resisting photoaging.
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3. Gentle Repair Extremely low irritation, with a risk factor of only 1, no need to establish tolerance. Can soothe the skin, maintain the integrity of the skin barrier, adapt to daily care of sensitive skin, and also have the effect of softening the skin, enhancing the skin feel of skincare products.
Common Application Products: High-end whitening essence oil, anti-aging essence, face cream, lotion, sunscreen products, post sun repair products, facial mask — especially suitable for "oil skin care" dosage forms. Can work together with nicotinamide, vitamin E derivatives, bose, peptides and other ingredients to enhance the efficacy of the product.
Recommended Dosage: 0.1%–2.0% is recommended for resident products (face cream, essence). The CIR assessment of the United States considers concentrations no higher than 4% safe for use. It is recommended to add no more than 0.05% to cleansing and shampoo products, and to further enhance stability by combining 0.1–0.3% tocopherol and disodium EDTA in the formula.
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Package
1kg / 5kg / 20kg / Bottle
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Storage
Store in a cool, dry, and well ventilated place, away from light and sealed. Keep away from strong acids, alkalis, and oxidants. Avoid mixing with odors and volatile chemicals. When stacking, keep away from the ground and walls to prevent moisture.
Frequently Asked Questions
QWhat is VC-IP and how does it differ from regular Vitamin C?
VC-IP (Ascorbyl Tetraisopalmitate) is a fat-soluble form of Vitamin C. Unlike water-soluble Vitamin C (L-Ascorbic Acid), VC-IP is highly stable, oil-compatible, and has a transdermal absorption rate 16.5 times higher, allowing it to penetrate the stratum corneum more effectively before being converted to active Vitamin C by skin enzymes.
QIs VC-IP suitable for sensitive skin?
Yes. VC-IP has an extremely low irritation risk factor of only 1, making it one of the gentlest active whitening ingredients available. It does not require a tolerance-building period and is suitable for daily use on sensitive skin, including skin that is intolerant to niacinamide.
QWhat is the recommended usage concentration of VC-IP in skincare formulations?
For leave-on products such as face creams and serums, a concentration of 0.1%–2.0% is recommended. The U.S. CIR assessment confirms concentrations up to 4% are safe. For rinse-off products like cleansers and shampoos, no more than 0.05% is advised.
QCan VC-IP be combined with other active ingredients?
Absolutely. VC-IP has excellent formula compatibility and works synergistically with nicotinamide, vitamin E derivatives, peptides, and other antioxidants. Combining 0.1–0.3% tocopherol and disodium EDTA in the formula can further enhance VC-IP's stability and overall product efficacy.
QHow should VC-IP be stored to maintain its quality?
VC-IP should be stored in a cool, dry, and well-ventilated area, away from direct light in a sealed container. It must be kept away from strong acids, alkalis, and oxidants. Avoid storing near odor-emitting or volatile chemicals, and ensure containers are kept off the ground and away from walls to prevent moisture absorption.
QIs VC-IP legally recognized as a whitening ingredient?
Yes. VC-IP has been officially listed as a legal whitening active ingredient in Japan, South Korea, and Taiwan, China. Its proven ability to inhibit tyrosinase activity and block melanin production at the source makes it a regulatory-approved and scientifically validated choice for whitening skincare formulations.




