Azelaic Acid CAS 123-99-9 - High-Quality Supplier from China | Reliable Factory Raw Material
Chemical Name: Azelaic Acid
CAS No.: 123-99-9
Molecular Formula: C9H16O4
Molecular Weight: 188.22
Appearance: Crystalline Powder
Sample: We offer free samples
Key Properties: Melting point is approximately 106°C and boiling point is 286°C (at 100 mmHg). Azelaic acid is slightly soluble in cold water (around 2.4 g/L at 20°C) but freely soluble in hot water, ethanol, propylene glycol, and ethyl acetate. This chemical is chemically stable, resistant to oxidation and decomposition, and exhibits typical reactions of dibasic carboxylic acids such as salt formation and esterification.
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,| Item | Specifications |
| Appearance | Crystalline powder |
| Moisture | ≤0.2% |
| Assay | ≥98% |
| Acid value | 585–610 |
| Melting point | 105–110℃ |
| Particle size | ≥60 mesh |
| Plumbum | ≤1 ppm |
| Arsenic | ≤1 ppm |
| Chromium | ≤1 ppm |
| Color | ≥ 95% |
| Color | ≥ 99% |
Inhibits Cutibacterium acnes (formerly P. acnes), regulates follicular keratinization, and exerts anti-inflammatory effects. Common formulations include 15% gel and 20% cream; recommended for topical use by the Chinese Guidelines for Acne Treatment.
Selectively inhibits tyrosinase in abnormal melanocytes to fade acne marks, post-inflammatory hyperpigmentation (PIH), and melasma. Its irritation potential is significantly lower than that of tretinoin or high-concentration AHAs.
Inhibits 5α-reductase to reduce sebum secretion. Suitable for oily, acne-prone skin and as adjunctive care for rosacea.
Gels, creams, moisturizers, serums, and masks.
- Plasticizers: Synthesis of Dioctyl Azelate (DOZ), Diisooctyl Azelate, etc. Used in PVC and rubber, offering excellent heat resistance, cold resistance, and electrical insulation properties; suitable for products in low-temperature environments.
- Lubricants / Synthetic Oils: Used as components for precision instruments and aviation hydraulic fluids.
- Coatings / Resins: Modified polyesters and alkyd resins to improve coating flexibility and weatherability.
Feed additives, electroplating brighteners, polymer crosslinking agents, etc.
- Cold Wave Lotions / Perm Solutions: Softens hair keratin and reshapes disulfide bonds to achieve permanent curling; serves as the core reducing agent in cold perms.
- Hair Straightening Creams / Relaxers: Cleaves disulfide bonds to soften hair, working in conjunction with neutralizers to achieve permanent straightening.
- Depilatory Creams / Lotions: Softens body hair keratin to facilitate easy removal; the preferred choice for mild depilatory products.
- Recommended Concentration: 5%–15% for perming/straightening; 2%–8% for depilatory use.
- Metal Corrosion Inhibition: Forms a protective FeS film in high-temperature brine/completion fluids to inhibit carbon steel corrosion (140–200℃).
- Chemical Analysis: Used as a masking agent and reducing agent for the photometric determination of ions such as iron, aluminum, silver, and tin.
- Material Modification: Serves as a thiolating agent for the preparation of adsorption materials and functional polymers.
- Electronic Cleaning: Acts as an auxiliary agent for metal surface treatment and cleaning.