Benzethonium Chloride CAS 121-54-0 - China Suppliers and Factory for High-Quality Chemical Products
Typical Properties
| Item | Specifications |
| Appearance | White fine powder or crystals |
| Identification | A white precipitate, which is insoluble in 2N nitric acid but soluble in 6N ammonium hydroxide |
| Assay | 97~103% |
| Melting range | 158~163℃ |
| Loss on drying | 0.5% max |
| PH | 5~6.5 |
| Residue on ignition | 0.1% max |
Benzethonium Chloride is a broad-spectrum, highly efficient, low-irritation, and stable quaternary ammonium cationic surfactant. Combining the triple functions of germicidal, preservative, and surfactant properties, it is widely used in pharmaceuticals, daily chemicals, disinfection, and personal care, serving as a core raw material for high-end disinfection and preservation systems.
Product Advantages
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1. Broad-Spectrum & High Efficiency
Effective against Gram-positive/negative bacteria, fungi, and enveloped viruses, providing long-lasting bacteriostasis for 4–8 hours.
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2. Low Irritation & High Safety
Significantly less irritating to the skin than Benzalkonium Chloride; mucosal-friendly and compliant with pharmacopoeia and cosmetic standards.
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3. Excellent Stability
Strong formulation compatibility, resistant to decomposition, long shelf life, and suitable for various dosage forms.
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4. Multifunctional
Combines germicidal, preservative, and surfactant properties in one, simplifying formulations and reducing costs.
Application Areas
1 Medicine & Healthcare
- Disinfection: Skin and mucous membrane disinfectants, surgical instrument disinfection, wound cleansing solutions.
- Preservation & Sterilization: Preservatives and bactericides for eye drops, oral rinses (mouthwashes), and feminine hygiene washes.
- Antibacterial Treatment: Used for antibacterial treatment of medical wipes, tampons, and dressings.
2 Daily Chemicals & Cosmetics (Core Application)
- Preservative Standards: ≤0.1% for leave-on products, ≤0.2% for rinse-off products (according to Chinese regulations).
- Hygiene Products: Facial cleansers, body washes, hand soaps, wet wipes, mouthwashes, and toothpaste.
- Skincare & Haircare: Preservation and antibacterial protection for lotions, creams, serums, and hair care products.
3 Personal Care & Household
- Personal Care: Baby wipes, feminine care washes, pet cleaning and disinfection.
- Home Care: Household surface disinfection, fabric antimicrobial treatment, and air fresheners.
4 Industrial & Others
- Industrial Processing: Antimicrobial finishing for textile printing and dyeing, leather preservation, and water treatment bacteriostasis.
- Food & Raw Materials: Cleaning of food processing equipment and preservation of cosmetic raw materials.
Package & Storage
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Package
1kg/aluminum foil bag, 25kg/cardboard drum
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Storage
Store in a cool, dry, and dark place, sealed
Frequently Asked Questions (FAQ)
Q What is Benzethonium Chloride and what is it used for?
Benzethonium Chloride is a quaternary ammonium cationic surfactant that combines germicidal, preservative, and surfactant properties. It is widely used in pharmaceuticals, daily chemicals, personal care products, cosmetics, and industrial applications as a broad-spectrum antimicrobial and preservative agent.
Q How does Benzethonium Chloride compare to Benzalkonium Chloride in terms of skin safety?
Benzethonium Chloride is significantly less irritating to the skin compared to Benzalkonium Chloride. It is mucosal-friendly and compliant with pharmacopoeia and cosmetic safety standards, making it a preferred choice for sensitive skin formulations and personal care products.
Q What is the recommended usage concentration in cosmetic products?
According to Chinese cosmetic regulations, the recommended concentration is ≤0.1% for leave-on products (such as lotions and creams) and ≤0.2% for rinse-off products (such as facial cleansers and body washes). Always refer to local regulatory guidelines for your specific market.
Q What types of microorganisms does Benzethonium Chloride effectively kill?
Benzethonium Chloride is effective against a broad spectrum of microorganisms, including Gram-positive bacteria, Gram-negative bacteria, fungi, and enveloped viruses. It provides long-lasting bacteriostatic effects for 4–8 hours after application.
Q How should Benzethonium Chloride be stored to maintain its quality?
Benzethonium Chloride should be stored in a cool, dry, and dark environment in a tightly sealed container. Proper storage ensures its stability, prevents decomposition, and maintains its efficacy throughout its shelf life.
Q What packaging options are available for Benzethonium Chloride?
Benzethonium Chloride is available in two packaging options: 1kg aluminum foil bags, suitable for laboratory or small-scale use, and 25kg cardboard drums, designed for industrial or bulk purchasing needs. Custom packaging may be available upon request.





