Benzethonium Chloride CAS 121-54-0 - Quality Chemical from China Suppliers & Factory
Typical Properties
| Item | Specifications |
| Appearance | White fine powder or crystals |
| Identification | A white precipitate, which is insoluble in 2N nitric acid but soluble in 6N ammonium hydroxide |
| Assay | 97~103% |
| Melting Range | 158~163℃ |
| Loss on Drying | 0.5% max |
| pH | 5~6.5 |
| Residue on Ignition | 0.1% max |
Benzethonium Chloride is a broad-spectrum, highly efficient, low-irritation, and stable quaternary ammonium cationic surfactant. Combining the triple functions of germicidal, preservative, and surfactant properties, it is widely used in pharmaceuticals, daily chemicals, disinfection, and personal care, serving as a core raw material for high-end disinfection and preservation systems.
Product Advantages
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1. Broad-Spectrum & High Efficiency
Effective against Gram-positive/negative bacteria, fungi, and enveloped viruses, providing long-lasting bacteriostasis for 4–8 hours.
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2. Low Irritation & High Safety
Significantly less irritating to the skin than Benzalkonium Chloride; mucosal-friendly and compliant with pharmacopoeia and cosmetic standards.
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3. Excellent Stability
Strong formulation compatibility, resistant to decomposition, long shelf life, and suitable for various dosage forms.
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4. Multifunctional
Combines germicidal, preservative, and surfactant properties in one, simplifying formulations and reducing costs.
Application Areas
💊 1. Medicine & Healthcare
- Disinfection: Skin and mucous membrane disinfectants, surgical instrument disinfection, wound cleansing solutions.
- Preservation & Sterilization: Preservatives and bactericides for eye drops, oral rinses (mouthwashes), and feminine hygiene washes.
- Antibacterial Treatment: Used for antibacterial treatment of medical wipes, tampons, and dressings.
🧴 2. Daily Chemicals & Cosmetics (Core Application)
- Preservative Standards: ≤0.1% for leave-on products, ≤0.2% for rinse-off products (according to Chinese regulations).
- Hygiene Products: Facial cleansers, body washes, hand soaps, wet wipes, mouthwashes, and toothpaste.
- Skincare & Haircare: Preservation and antibacterial protection for lotions, creams, serums, and hair care products.
🏠 3. Personal Care & Household
- Personal Care: Baby wipes, feminine care washes, pet cleaning and disinfection.
- Home Care: Household surface disinfection, fabric antimicrobial treatment, and air fresheners.
🏭 4. Industrial & Others
- Industrial Processing: Antimicrobial finishing for textile printing and dyeing, leather preservation, and water treatment bacteriostasis.
- Food & Raw Materials: Cleaning of food processing equipment and preservation of cosmetic raw materials.
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Package
1 kg / aluminum foil bag
25 kg / cardboard drum
25 kg / cardboard drum
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Storage
Store in a cool, dry, and dark place, sealed
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Frequently Asked Questions (FAQ)
QWhat is Benzethonium Chloride and what is it mainly used for?
Benzethonium Chloride is a quaternary ammonium cationic surfactant with broad-spectrum antimicrobial activity. It is primarily used as a germicide, preservative, and surfactant in pharmaceuticals, cosmetics, daily chemical products, personal care items, and industrial applications.
QHow does Benzethonium Chloride differ from Benzalkonium Chloride?
While both are quaternary ammonium compounds with antimicrobial properties, Benzethonium Chloride is significantly less irritating to skin and mucous membranes compared to Benzalkonium Chloride. It is considered safer for use in leave-on products, eye drops, and formulations requiring mucosal contact.
QWhat is the recommended usage concentration for cosmetic products?
According to Chinese cosmetic regulations, the recommended usage concentration is ≤0.1% for leave-on products (such as lotions and creams) and ≤0.2% for rinse-off products (such as shampoos and body washes). Always verify applicable local regulatory limits before formulating.
QWhat types of microorganisms does Benzethonium Chloride work against?
Benzethonium Chloride is effective against a broad spectrum of microorganisms, including Gram-positive bacteria, Gram-negative bacteria, fungi, and enveloped viruses. It provides sustained bacteriostatic activity for approximately 4–8 hours after application.
QHow should Benzethonium Chloride be stored to maintain its quality?
It should be stored in a cool, dry, and dark environment in a tightly sealed container. Proper storage ensures its stability and extends its shelf life. Avoid exposure to direct sunlight, high temperatures, or moisture.
QWhat packaging options are available for Benzethonium Chloride?
Benzethonium Chloride is available in two standard packaging options: 1 kg aluminum foil bags for small-scale or laboratory use, and 25 kg cardboard drums for bulk industrial or commercial applications. Custom packaging may be available upon request.





