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Hydroxyapatite CAS 1306-06-5 | High-Quality Calcium Phosphate from China Suppliers and Factory
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Chemical Name: Hydroxyapatite
CAS No.: 1306-06-5
Molecular Formula: Ca5HO13P3
Molecular Structure:
Molecular Weight: 502.31
Appearance: White powder
Sample: Free samples available for testing
Melting Point: 1100 °C (lit.)
Density: 3.076 g/cm3 (at 18 °C)
Solubility: Insoluble in water and ethanol, soluble in acid, slightly soluble in alkali
Our Hydroxyapatite, sourced from trusted China suppliers and produced in our state-of-the-art factory, meets the highest quality standards for various applications. If you require high-purity Hydroxyapatite, contact us today for free samples and to learn more about our competitive pricing.
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Typical Properties
| Item | Specifications |
| Appearance | White powder |
| Assay | ≥96% |
| Average Particle Size | 20 nm, 40 nm, 60 nm |
| Ca:P mg/kg | GBB 1871.1 |
| As mg/kg | Pharmacopoeia standards |
| Cd mg/kg | GB10724 |
| Hg mg/kg | GB9723 |
| Pb mg/kg | GB10724 |
| The total amount of heavy metal elements | Pharmacopoeia standards |
Core Physicochemical Properties
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🦴1. Excellent Biocompatibility Its composition is consistent with human bone tissue, making it non-toxic, non-irritating, and free from immune rejection.
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🔬2. Osteoconductivity Capable of guiding new bone growth to achieve bone tissue repair and integration.
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🧲3. High Adsorption Capacity Possesses strong adsorption capabilities for heavy metal ions, fluoride ions, proteins, and bacteria.
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🔥4. Thermal Resistance & Chemical Stability Heat resistant and stable against acids and alkalis, making it difficult to decompose.
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🧪5. Tunable Porous Structure Can be fabricated into porous materials with high specific surface area, suitable for adsorption and carrier applications.
Application
1
Oral Care (Mainstream Consumer Use)
Additives: Used as an additive in toothpaste and mouthwash.
Benefits: Repairs enamel, desensitizes, prevents cavities, whitens teeth, and reduces plaque.
Target Audience: Serves as a fluoride substitute, suitable for children and individuals with sensitive teeth.
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Biomedical Materials
Bone Repair: Used as bone defect fillers, artificial bone, and bone cement.
Implants: Applied as coatings for dental implants and for surface modification of orthopedic implants.
Medical Supplies: Functions as a drug sustained-release carrier and surgical hemostatic material.
Dental Applications: Used for dental root canal filling and alveolar bone repair.
3
Environmental Protection & Water Treatment
Purification: Removes fluoride ions and heavy metals (Pb, Cd, Cu, Ni, etc.) from water.
Treatment: Used for deep treatment of industrial wastewater and purification of drinking water.
4
Chemical Industry & Separation
Purification: Serves as chromatography packing for the separation and purification of proteins, enzymes, and nucleic acids.
Carriers: Used as a catalyst carrier and immobilized enzyme carrier.
Media: Acts as a chromatographic separation medium.
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Other Applications
Food: Used as a food additive (calcium fortifier).
Cosmetics: Serves as a cosmetic filler and skincare ingredient.
Materials: Used as an additive in ceramic materials and bio-glass.
Package & Storage
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Package
1kg/bag, 5kg/bag, 25kg/drum
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Storage
Sealed, dry, cool place — moisture-proof and sun-protected
❓ Frequently Asked Questions (FAQ)
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What is nano-hydroxyapatite and how does it differ from regular hydroxyapatite?
Nano-hydroxyapatite (nHA) is a nanoscale form of hydroxyapatite with particle sizes typically ranging from 20 nm to 60 nm. Compared to conventional hydroxyapatite, it has a significantly larger specific surface area, higher reactivity, and superior biocompatibility — more closely mimicking the mineral composition of natural human bone and tooth enamel.
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Is nano-hydroxyapatite safe for use in toothpaste and oral care products?
Yes. Nano-hydroxyapatite is non-toxic, non-irritating, and biocompatible. It is widely used as a fluoride-free alternative in toothpaste and mouthwash. It is particularly suitable for children and individuals with sensitive teeth, as it helps repair enamel, reduce sensitivity, and prevent cavities without the risks associated with fluoride overexposure.
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What particle sizes are available and how does particle size affect performance?
The product is available in three particle sizes: 20 nm, 40 nm, and 60 nm. Smaller particle sizes generally offer higher surface area and stronger adsorption capacity, which is beneficial for biomedical and water treatment applications. Larger particles may be preferred for specific structural or carrier applications. The optimal size depends on the intended use.
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Can nano-hydroxyapatite be used for heavy metal removal in water treatment?
Yes. Nano-hydroxyapatite exhibits strong adsorption capacity for heavy metal ions including lead (Pb), cadmium (Cd), copper (Cu), and nickel (Ni), as well as fluoride ions. It is used in both industrial wastewater deep treatment and drinking water purification processes, offering an effective and environmentally friendly solution.
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What are the storage requirements for nano-hydroxyapatite powder?
Nano-hydroxyapatite powder should be stored in a sealed container in a dry, cool place, away from moisture and direct sunlight. Proper storage prevents clumping, contamination, and degradation of product quality. Available packaging options include 1 kg/bag, 5 kg/bag, and 25 kg/drum to suit various usage scales.
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What industries and sectors commonly use nano-hydroxyapatite?
Nano-hydroxyapatite is used across a wide range of industries including oral care (toothpaste, mouthwash), biomedical engineering (bone repair, dental implants, drug delivery), environmental protection (water purification), chemical and biochemical separation (chromatography, enzyme carriers), food manufacturing (calcium fortifier), cosmetics, and advanced materials such as ceramics and bio-glass.