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Hydroxyapatite CAS 1306-06-5 - High-Quality White Powder from China Suppliers and Factory
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Chemical Name: Hydroxyapatite
CAS No.: 1306-06-5
Molecular Formula: Ca5HO13P3
Molecular Structure:
Molecular Weight: 502.31
Appearance: White powder
Sample: Free samples are available upon request
Melting Point: 1100 °C (lit.)
Density: 3.076 g/cm3 (at 18 °C)
Solubility: Difficult to dissolve in water and ethanol; soluble in acid and slightly soluble in alkali
As a leading China supplier and manufacturer, our factory provides premium quality Hydroxyapatite that meets various industrial standards. This versatile chemical compound is extensively used in pharmaceuticals, biotechnology, and cosmetics, making it a valuable addition to your product line. Our commitment to quality ensures that you receive the best Hydroxyapatite for your needs, available in convenient sample sizes.
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Typical Properties
| Item | Specifications |
| Appearance | White powder |
| Assay | ≥96% |
| Average Particle Size | 20 nm, 40 nm, 60 nm |
| Ca:P mg/kg | GBB 1871.1 |
| As mg/kg | Pharmacopoeia standards |
| Cd mg/kg | GB10724 |
| Hg mg/kg | GB9723 |
| Pb mg/kg | GB10724 |
| Total Heavy Metal Elements | Pharmacopoeia standards |
Core Physicochemical Properties
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1. Excellent Biocompatibility
Its composition is consistent with human bone tissue, making it non-toxic, non-irritating, and free from immune rejection.
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2. Osteoconductivity
Capable of guiding new bone growth to achieve bone tissue repair and integration.
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3. High Adsorption Capacity
Possesses strong adsorption capabilities for heavy metal ions, fluoride ions, proteins, and bacteria.
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4. Thermal Resistance & Chemical Stability
Heat resistant and stable against acids and alkalis, making it difficult to decompose.
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5. Tunable Porous Structure
Can be fabricated into porous materials with high specific surface area, suitable for adsorption and carrier applications.
Application
🦷 1. Oral Care
- Additives: Used as an additive in toothpaste and mouthwash.
- Benefits: Repairs enamel, desensitizes, prevents cavities, whitens teeth, and reduces plaque.
- Target Audience: Serves as a fluoride substitute, suitable for children and individuals with sensitive teeth.
🏥 2. Biomedical Materials
- Bone Repair: Used as bone defect fillers, artificial bone, and bone cement.
- Implants: Applied as coatings for dental implants and surface modification of orthopedic implants.
- Medical Supplies: Functions as a drug sustained-release carrier and surgical hemostatic material.
- Dental: Used for dental root canal filling and alveolar bone repair.
💧 3. Environmental Protection & Water Treatment
- Purification: Removes fluoride ions and heavy metals (Pb, Cd, Cu, Ni, etc.) from water.
- Treatment: Used for deep treatment of industrial wastewater and purification of drinking water.
⚗️ 4. Chemical Industry & Separation
- Purification: Serves as chromatography packing for separation and purification of proteins, enzymes, and nucleic acids.
- Carriers: Used as a catalyst carrier and immobilized enzyme carrier.
- Media: Acts as a chromatographic separation medium.
🌐 5. Other Applications
- Food: Used as a food additive (calcium fortifier).
- Cosmetics: Serves as a cosmetic filler and skincare ingredient.
- Materials: Used as an additive in ceramic materials and bio-glass.
Package & Storage
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Package
1 kg/bag | 5 kg/bag | 25 kg/drum
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Storage
Sealed, dry, cool place — moisture-proof and sun-protected
Frequently Asked Questions
Q What is nano-hydroxyapatite and how does it differ from regular hydroxyapatite?
Nano-hydroxyapatite (nHA) is a nanoscale form of hydroxyapatite with particle sizes typically ranging from 20 to 60 nm. Its ultra-small particle size provides a significantly higher specific surface area compared to conventional hydroxyapatite, resulting in superior bioactivity, adsorption capacity, and faster integration with biological tissues.
Q Is nano-hydroxyapatite safe for use in toothpaste and oral care products?
Yes. Nano-hydroxyapatite is recognized as a safe and effective ingredient in oral care. Its composition mirrors that of natural tooth enamel and bone mineral, making it non-toxic and non-irritating. It is widely used as a fluoride alternative in toothpaste and mouthwash, and is particularly suitable for children and individuals with sensitive teeth.
Q What particle sizes are available and how do they affect performance?
Our nano-hydroxyapatite is available in three particle sizes: 20 nm, 40 nm, and 60 nm. Smaller particle sizes offer a greater surface area and higher reactivity, which can be advantageous for biomedical and adsorption applications. Larger particles may provide improved structural stability and are often preferred for certain material science and ceramic applications.
Q Can nano-hydroxyapatite be used for heavy metal removal in water treatment?
Yes. Nano-hydroxyapatite exhibits strong adsorption capabilities for heavy metal ions such as lead (Pb), cadmium (Cd), copper (Cu), and nickel (Ni), as well as fluoride ions. It is effectively used in both industrial wastewater deep treatment and drinking water purification systems.
Q What packaging options are available and what are the storage requirements?
Nano-hydroxyapatite is available in 1 kg/bag, 5 kg/bag, and 25 kg/drum packaging to suit different procurement needs. For storage, the product should be kept in a sealed container in a dry, cool location, away from moisture and direct sunlight, to preserve its physicochemical properties and extend shelf life.
Q Does nano-hydroxyapatite meet pharmacopoeia and international quality standards?
Yes. Our nano-hydroxyapatite complies with relevant pharmacopoeia standards for heavy metal content (As, Hg, total heavy metals) and adheres to Chinese national standards including GB10724 and GB9723. The assay purity is ≥96%, ensuring consistent quality suitable for pharmaceutical, medical, and food-grade applications.