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Kojic Acid Dipalmitate CAS 79725-98-7 - China Suppliers & Factory - High-Quality White Crystal for Cosmetics
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Kojic Acid Dipalmitate CAS 79725-98-7 - China Suppliers & Factory - High-Quality White Crystal for Cosmetics

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Chemical Name: Kojic Acid Dipalmitate
CAS No.: 79725-98-7
Molecular Formula: C38H66O6
Molecular Weight: 618.93
Appearance: White sheet crystal
Sample: Free samples available upon request.
Kojic Acid Dipalmitate is a lipid-soluble compound that dissolves in mineral oils, esters, and hot ethanol, making it ideal for various cosmetic and pharmaceutical applications. However, it is insoluble in water. As a leading China supplier and factory, we ensure the highest quality and purity of our Kojic Acid Dipalmitate, catering to the needs of our clients in the beauty and health industries. Contact us today for more information on our products and to request a sample.

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    Typical Properties
    Item Specifications
    Appearance White sheet crystal
    Assay ≥98.0%
    Melting point 92~96℃
    Loss on drying ≤0.5%
    Ignition residue ≤0.5%
    Color reaction of ferric chloride Negative
    Heavy metal ≤10ppm
    Arsenic ≤2ppm
    Pathogen Bacteria: ≤300 cfu/g  |  Fungus: ≤100 cfu/g
    Core Characteristics & Advantages
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    1. Ultimate Stability

    It solves the fatal flaws of traditional Kojic Acid, which is sensitive to light and heat and prone to discoloration.

    Mechanism: The active hydroxyl group is esterified and blocked by palmitic acid, making it highly stable against light, heat, oxygen, and metal ions.

    Data: In accelerated testing (45°C / 60% RH for 3 months), the active retention rate is >90% (compared to only 58% for Kojic Acid).

    Benefit: It resists yellowing and loss of efficacy in formulations without requiring large amounts of additional stabilizers.

    2. Highly Efficient Whitening

    Tyrosinase Inhibition: By chelating the copper ions (Cu²⁺) at the enzyme's active center, it strongly blocks the key rate-limiting step of melanin synthesis. Its inhibition efficiency is superior to that of Kojic Acid and Arbutin.

    Blocking Melanin Production: Reduces the formation of spots and dullness from the source, with an efficacy rate exceeding 80%.

    Gentle Brightening: Also offers antioxidant benefits, improving uneven skin tone and aging-related dullness.

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    3. Safety & Low Irritation

    Structure: Its lipid-soluble structure reduces skin penetration irritation, eliminating the burning sensation associated with traditional Kojic Acid.

    Patch Test: At 2% concentration, it causes no irritation to healthy skin. The irritation index for sensitive skin is only 0.8 (compared to 2.3 for Kojic Acid).

    Usage: Non-photosensitive, safe for daytime use, and carries no risk of rebound hyperpigmentation.

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    4. Excellent Formulation Compatibility

    Solubility: Being lipid-soluble, it easily integrates into oil-phase systems like creams and lotions, making it formulation-friendly.

    Compatibility: It does not conflict with most preservatives, sunscreens, vitamins, and plant extracts.

    Penetration: It has strong penetration power, effectively reaching skin targets.

    Main Efficacy & Applications
    Core Efficacy
    • Whitening & Spot Fading: Fades melasma, age spots, acne marks, and post-inflammatory hyperpigmentation (PIH).
    • Brightening Skin Tone: Improves dullness and sallow complexion, leaving the skin translucent and fair.
    • Antioxidant: Scavenges free radicals and assists in preventing photo-aging.
    Application Areas (Cosmetics)
    • Whitening Creams / Serums: Focus on spot fading and brightening.
    • Spot Correctors: Targets stubborn pigmentation and acne marks.
    • Sunscreen / Primers: Synergistic whitening effect to prevent tanning.
    • Body Lotions / Hand Creams: All-over body whitening.
    • Makeup / Foundation: Brightens complexion while providing concealing and skin-nourishing benefits.
    Package & Storage
    📦
    Package
    25 kg / drum
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    Storage
    Store in a cool, dry, and dark place in a sealed container.
    Frequently Asked Questions
    Q
    What is Kojic Acid Dipalmitate and how does it differ from regular Kojic Acid?
    Kojic Acid Dipalmitate is a stable ester derivative of Kojic Acid, formed by esterifying the active hydroxyl group with palmitic acid. Unlike regular Kojic Acid, it is highly resistant to light, heat, and oxidation, with an active retention rate exceeding 90% in accelerated stability testing — compared to only 58% for standard Kojic Acid.
    Q
    Is Kojic Acid Dipalmitate safe for sensitive skin?
    Yes. Its lipid-soluble structure reduces skin penetration irritation significantly. At a 2% concentration, it causes no irritation to healthy skin, and the irritation index for sensitive skin is only 0.8 — much lower than the 2.3 recorded for traditional Kojic Acid. It is also non-photosensitive and safe for daytime use.
    Q
    What types of cosmetic formulations is Kojic Acid Dipalmitate suitable for?
    Due to its lipid-soluble nature, it integrates easily into oil-phase systems such as creams, lotions, serums, sunscreens, primers, body lotions, hand creams, and foundations. It is compatible with most preservatives, sunscreens, vitamins, and plant extracts.
    Q
    How does Kojic Acid Dipalmitate achieve its whitening effect?
    It works by chelating the copper ions (Cu²⁺) at the active center of tyrosinase, blocking the key rate-limiting step of melanin synthesis. This mechanism delivers an efficacy rate exceeding 80% in blocking melanin production, and its inhibition efficiency is superior to both Kojic Acid and Arbutin.
    Q
    What are the storage requirements for Kojic Acid Dipalmitate?
    It should be stored in a cool, dry, and dark place in a sealed container to maintain its stability and active ingredient integrity. Proper storage prevents premature degradation and ensures the product remains effective throughout its shelf life.
    Q
    What is the standard packaging specification and minimum purity of Kojic Acid Dipalmitate?
    Kojic Acid Dipalmitate is supplied in 25 kg drums. The standard assay purity is ≥98.0%, with a melting point of 92–96°C and heavy metal content of ≤10 ppm, ensuring high-quality pharmaceutical and cosmetic grade material.

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