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Sodium L-Pyroglutamate CAS 28874-51-3 - Leading China Suppliers & Factory for Natural Moisturizing Factors
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Sodium L-Pyroglutamate CAS 28874-51-3 - Leading China Suppliers & Factory for Natural Moisturizing Factors

Chemical Name: Sodium L-pyroglutamate, CAS No.: 28874-51-3, Molecular Formula: C5H6NNaO3, Molecular Weight: 151.1, Appearance: Clear transparent liquid, Sample: Free samples are available, Sodium L-pyroglutamate, a valuable ingredient derived from the cyclization of natural L-glutamic acid, plays a crucial role in Natural Moisturizing Factors (NMF). As a trusted chemical compound, it is widely utilized in various cosmetic and skincare formulations to enhance hydration and skin health, As a leading supplier and manufacturer in China, we take pride in our high-quality production standards and commitment to excellence. Our factory ensures the availability of premium Sodium L-pyroglutamate, catering to diverse industry needs. Explore our products today and benefit from free samples to experience the quality firsthand

    Typical Properties
    Item Specifications
    Appearance Clear transparent liquid
    PH 6.5~7.5
    Heavy Metal 10ppm
    Assay 50%~55%
    Product Features & Efficacy
    1
    High-Efficiency Hydration & Moisture Locking
    As a vital component of the skin's Natural Moisturizing Factors (NMF), PCA-Na possesses powerful hygroscopic and moisture-locking capabilities. It attracts moisture from the air and minimizes transepidermal water loss, offering significantly superior hydration compared to traditional humectants like glycerin and propylene glycol.
    2
    Gentle, Skin-Friendly & Barrier Repair
    Highly compatible with human skin, it is mild and non-irritating. It enhances stratum corneum hydration, alleviates dryness, roughness, and flaking, and helps repair damaged skin barriers, making it ideal for formulations targeting sensitive and dry skin.
    3
    Soft Skin Feel & Texture Enhancement
    It imparts a fresh, non-sticky sensation, leaving the skin soft, smooth, and free from tightness. It is widely used to elevate the sensory experience (skin feel) of skincare and personal care products.
    4
    Antioxidant & Soothing Properties
    It assists in antioxidant protection and alleviates discomfort caused by external stressors, thereby improving the overall health of the skin.
    Main Application Areas
    • Skincare: Toners, serums, lotions, creams, masks, and hydrating gels.
    • Hair Care: Shampoos, conditioners, and hair masks (helps tame frizz and dryness while boosting hair hydration).
    • Cleansing: Facial cleansers and body washes (provides gentle hydration to prevent tightness after washing).
    • Daily Chemicals & Others: Body lotions, hand creams, baby care products, and aftershaves.
    Package
    📦
    Packaging Options
    200kg/drum  |  25kg/drum
    Storage
    🌡️
    Storage Conditions
    Sealed and stored in a cool, dry place
    Frequently Asked Questions
    What is PCA-Na and where does it come from?
    PCA-Na (Sodium PCA) is the sodium salt of pyrrolidone carboxylic acid. It is a naturally occurring component of the skin's Natural Moisturizing Factors (NMF), responsible for maintaining optimal moisture levels in the stratum corneum. It can be derived naturally or produced synthetically for cosmetic use.
    How does PCA-Na compare to glycerin as a humectant?
    PCA-Na offers significantly superior hydration performance compared to traditional humectants such as glycerin and propylene glycol. It attracts moisture more effectively from the environment and minimizes transepidermal water loss (TEWL), resulting in longer-lasting and more intensive skin hydration.
    Is PCA-Na suitable for sensitive skin formulations?
    Yes. PCA-Na is highly compatible with human skin, mild, and non-irritating. It is especially well-suited for formulations targeting sensitive, dry, or compromised skin, as it helps repair damaged skin barriers and alleviates dryness, roughness, and flaking.
    At what concentration should PCA-Na be used in cosmetic formulations?
    PCA-Na (50%~55% assay) is typically used at a concentration of 1%–5% in finished cosmetic formulations depending on the product type and desired hydration effect. It can be incorporated into both rinse-off and leave-on products across skincare, hair care, and cleansing categories.
    What product types can PCA-Na be incorporated into?
    PCA-Na is highly versatile and can be used in a wide range of products including toners, serums, lotions, creams, masks, hydrating gels, shampoos, conditioners, hair masks, facial cleansers, body washes, body lotions, hand creams, baby care products, and aftershaves.
    What are the recommended storage conditions for PCA-Na?
    PCA-Na should be stored sealed in a cool, dry place, away from direct sunlight and heat sources. Proper storage helps maintain its stability, clarity, and performance over time. Available packaging options include 200kg/drum and 25kg/drum to suit different production scales.

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