Sodium L-Pyroglutamate CAS 28874-51-3 - Leading China Suppliers & Factory for Natural Moisturizing Factors
Typical Properties
| Item | Specifications |
| Appearance | Clear transparent liquid |
| PH | 6.5~7.5 |
| Heavy Metal | 10ppm |
| Assay | 50%~55% |
Product Features & Efficacy
1
High-Efficiency Hydration & Moisture Locking
As a vital component of the skin's Natural Moisturizing Factors (NMF), PCA-Na possesses powerful hygroscopic and moisture-locking capabilities. It attracts moisture from the air and minimizes transepidermal water loss, offering significantly superior hydration compared to traditional humectants like glycerin and propylene glycol.
2
Gentle, Skin-Friendly & Barrier Repair
Highly compatible with human skin, it is mild and non-irritating. It enhances stratum corneum hydration, alleviates dryness, roughness, and flaking, and helps repair damaged skin barriers, making it ideal for formulations targeting sensitive and dry skin.
3
Soft Skin Feel & Texture Enhancement
It imparts a fresh, non-sticky sensation, leaving the skin soft, smooth, and free from tightness. It is widely used to elevate the sensory experience (skin feel) of skincare and personal care products.
4
Antioxidant & Soothing Properties
It assists in antioxidant protection and alleviates discomfort caused by external stressors, thereby improving the overall health of the skin.
Main Application Areas
- Skincare: Toners, serums, lotions, creams, masks, and hydrating gels.
- Hair Care: Shampoos, conditioners, and hair masks (helps tame frizz and dryness while boosting hair hydration).
- Cleansing: Facial cleansers and body washes (provides gentle hydration to prevent tightness after washing).
- Daily Chemicals & Others: Body lotions, hand creams, baby care products, and aftershaves.
Package
📦
Packaging Options
200kg/drum | 25kg/drum
Storage
🌡️
Storage Conditions
Sealed and stored in a cool, dry place
Frequently Asked Questions
What is PCA-Na and where does it come from?
PCA-Na (Sodium PCA) is the sodium salt of pyrrolidone carboxylic acid. It is a naturally occurring component of the skin's Natural Moisturizing Factors (NMF), responsible for maintaining optimal moisture levels in the stratum corneum. It can be derived naturally or produced synthetically for cosmetic use.
How does PCA-Na compare to glycerin as a humectant?
PCA-Na offers significantly superior hydration performance compared to traditional humectants such as glycerin and propylene glycol. It attracts moisture more effectively from the environment and minimizes transepidermal water loss (TEWL), resulting in longer-lasting and more intensive skin hydration.
Is PCA-Na suitable for sensitive skin formulations?
Yes. PCA-Na is highly compatible with human skin, mild, and non-irritating. It is especially well-suited for formulations targeting sensitive, dry, or compromised skin, as it helps repair damaged skin barriers and alleviates dryness, roughness, and flaking.
At what concentration should PCA-Na be used in cosmetic formulations?
PCA-Na (50%~55% assay) is typically used at a concentration of 1%–5% in finished cosmetic formulations depending on the product type and desired hydration effect. It can be incorporated into both rinse-off and leave-on products across skincare, hair care, and cleansing categories.
What product types can PCA-Na be incorporated into?
PCA-Na is highly versatile and can be used in a wide range of products including toners, serums, lotions, creams, masks, hydrating gels, shampoos, conditioners, hair masks, facial cleansers, body washes, body lotions, hand creams, baby care products, and aftershaves.
What are the recommended storage conditions for PCA-Na?
PCA-Na should be stored sealed in a cool, dry place, away from direct sunlight and heat sources. Proper storage helps maintain its stability, clarity, and performance over time. Available packaging options include 200kg/drum and 25kg/drum to suit different production scales.




