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Tranexamic Acid CAS 1197-18-8 - High-Quality Supplier & Factory in China for White Crystalline Powder
Typical Properties
| Item | Specifications |
| Content | 99.0% min |
| PH | 7.0~8.0 |
| Loss on drying | ≤0.5% |
| Residue on ignition | ≤0.1% |
| Heavy metals | ≤10ppm |
| Sulphate | ≤0.07% |
| Chloride | ≤140ppm |
| Arsenic | ≤2ppm |
Core Mechanisms of Action
🩸 Medical Hemostasis
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Antifibrinolytic Effect: It competitively inhibits the adsorption of plasminogen onto fibrin, preventing its activation into plasmin. Simultaneously, it directly inhibits plasmin activity, protecting fibrin from degradation and achieving potent hemostasis.
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Anti-inflammatory / Anti-edema: It inhibits plasmin-mediated activation of the complement system (C1), reducing the release of inflammatory mediators. This mechanism is utilized in the treatment of hereditary angioedema.
✨ Skincare & Whitening
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Inhibition of Melanogenesis: It blocks signal transduction between melanocytes and keratinocytes and inhibits tyrosinase activity, thereby reducing melanin synthesis through multiple pathways.
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Improvement of Hyperpigmentation: It inhibits angiogenesis and alleviates post-inflammatory hyperpigmentation (PIH), showing significant efficacy against melasma, acne marks, and age spots.
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Repair & Soothing: It improves skin barrier function and reduces redness and sensitivity, being mild and non-irritating.
🧴 Applications in Daily Chemical & Skincare
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Whitening & Spot Reduction: Incorporated into serums, creams, and masks to target melasma, sun spots, acne marks, and dull complexion.
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Repair & Soothing: Formulated in products for sensitive and redness-prone skin to improve inflammation and vascular abnormalities.
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Anti-aging & Brightening: Combined with antioxidant ingredients to enhance skin transparency and radiance.
Package & Storage
📦
Package
25 kg / Drum
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Storage
Warehouse ventilation, low temperature drying
💬 Frequently Asked Questions
Q What is the minimum purity content of this product?
A The product has a minimum content of 99.0%, ensuring high purity suitable for both pharmaceutical and cosmetic applications.
Q How does this ingredient work for skin whitening?
A It works through multiple pathways: blocking signal transduction between melanocytes and keratinocytes, inhibiting tyrosinase activity, suppressing angiogenesis, and alleviating post-inflammatory hyperpigmentation (PIH) to reduce melanin synthesis effectively.
Q Is this ingredient safe for sensitive skin?
A Yes. It is mild and non-irritating. It improves skin barrier function, reduces redness and sensitivity, and is suitable for formulation in products designed for sensitive and redness-prone skin.
Q What types of skincare products can this ingredient be incorporated into?
A It can be incorporated into a wide range of products including serums, creams, and masks targeting melasma, sun spots, acne marks, dull complexion, and anti-aging formulations.
Q What are the packaging and storage requirements?
A The product is packaged in 25 kg drums. It should be stored in a well-ventilated warehouse under low temperature and dry conditions to maintain its stability and quality.
Q What is the medical application of this ingredient beyond skincare?
A In medical applications, it functions as a potent antifibrinolytic agent for hemostasis and also inhibits plasmin-mediated complement activation, making it effective in treating hereditary angioedema and reducing inflammatory responses.